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Genetic Algorithms for Optimized Diagnosis of Alzheimer’s Disease and Frontotemporal Dementia Using Fluorodeoxyglucose Positron Emission Tomography Imaging

Genetic algorithms have a proven capability to explore a large space of solutions, and deal with very large numbers of input features. We hypothesized that the application of these algorithms to 18F-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) may help in diagnosis of Alzheimer’s disease (AD) and Frontotemporal Dementia (FTD) by selecting the most meaningful features and automating diagnosis.